Composition and Mechanism of Action

•  Amlodipine (5 mg per tablet): A calcium channel blocker that relaxes and widens blood vessels, improving blood flow and reducing the heart’s workload.
• Losartan (50 mg per tablet): An angiotensin II receptor blocker (ARB) that prevents blood vessels from tightening, lowering blood pressure and protecting organs such as the heart and kidneys.

The combination works synergistically to effectively manage hypertension and may lower the risk of heart attack, stroke, and kidney complications, particularly in patients with underlying conditions like diabetes or chronic kidney disease.

Uses

• Management of high blood pressure (hypertension).
• Reduction of cardiovascular risks associated with long-term high blood pressure.
• Protection of kidney function in susceptible individuals.

Dosage and Administration

The usual dose is one tablet daily, which can be taken with or without food. It is important to follow your healthcare provider’s instructions and maintain consistent timing for optimal blood pressure control.

Common Side Effects

• Dizziness or lightheadedness (especially when starting the medication)
• Swelling (edema), usually in ankles or feet due to amlodipine
• Fatigue and headache Cough (less common than with ACE inhibitors)
• Serious side effects may include severe allergic reactions, liver abnormalities, or significant drops in blood pressure. Patients with kidney or liver disease, heart problems, or elevated potassium should use caution.

Precautions

Pregnant or breastfeeding women should avoid unless prescribed by a professional.

Monitor blood pressure and kidney function regularly. Discuss all medications and supplements with your doctor to avoid potential interactions